Nottingham

2021

• The Nottingham Multiple Sclerosis Research Group helped design and lead an audit as part of the UK MS trials and registries consortium: A multicentre audit on the use of MRI in the monitoring and management of people with Multiple Sclerosis

2020

• Chou IJ, Kuo CF, Tanasescu R, Tench CR, Tiley CG, Constantinescu CS, Whitehouse WP. Comorbidity in multiple sclerosis: its temporal relationships with disease onset and dose effect on mortality. 2020. Eur J Neurol. 27(1):105-112. doi: 10.1111/ene.14040.
• Lincoln, N.B., Bradshaw, L.E., Constantinescu, C., Day, F., Drummond, A.E.R., Fitzsimmons, D., Harris, H., Montgomery, A.A & das Nair, R. (2020). Cognitive Rehabilitation for Attention and Memory in people with Multiple Sclerosis: a randomised controlled trial (CRAMMS). Health Technology Assessment, 24(4):1-182. doi: 10.3310/hta24040.
• Meek., C., Topcu, G., Moghaddam, N., & das Nair, R. (2020). Experiences of adjustment to secondary progressive multiple sclerosis: A meta-ethnographic systematic review. Disability & Rehabilitation. DOI: 10.1080/09638288.2020.1734105
• Maple PAC, Tanasescu R, Gran B, Constantinescu CS. A different response to cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infection in UK people with multiple sclerosis (PwMS) compared to controls. 2020. J Infect. 80(3):320-325. doi: 10.1016/j.jinf.2019.10.017
• Papathanasiou A, Tanasescu R, Davis J, Rocha MF, Singhal S, O'Donoghue MF, Constantinescu CS. MOG-IgG-associated demyelination: focus on atypical features, brain histopathology and concomitant autoimmunity. 2020. J Neurol. 267(2):359-368. doi: 10.1007/s00415-019-09586-5
• Parker, L-S., Topcu, D., De Boos, D., & das Nair, R. (2020). The notion of ‘invisibility’ in people’s experiences of the symptoms of multiple sclerosis: a systematic meta-synthesis. Disability & Rehabilitation. DOI: 10.1080/09638288.2020.1741698
• Potter, J-J., Golijana-Moghaddam, N., Evangelou, N., Mhizha-Murira, J., & das Nair, R. (2020). Self-help Acceptance and Commitment Therapy for Carers of People with Multiple Sclerosis: A Feasibility Randomised Controlled Trial. Journal of Clinical Psychology in Medical Settings.  DOI: 10.1007/s10880-020-09711-x
• Welton T, Constantinescu CS, Auer DP, Dineen RA. Graph theoretic analysis of brain connectomics in multiple sclerosis: reliability and relationship to cognition. 2020 Brain Connect. February 20, DOI: 10/1089/brain.2019.0717. Epub

2019

• Alrouji M, Manouchehrinia A, Gran B, Constantinescu CS, 2019. Effects of cigarette smoke on immunity, neuroinflammation and multiple sclerosis. J Neuroimmunol 329:24-34.
• Barker, A., Lincoln, N. B., Hunt, N., & das Nair, R. (2019). The Experience of Identity Change in People who Reported Having a Diagnosis of Multiple Sclerosis: A Qualitative Enquiry. International Journal of MS Care, 21(5): 235–242.
• Chou IJ, Kuo CF, Tanasescu R, Tench CR, Tiley CG, Constantinescu CS, Whitehouse WP. Epilepsy and associated mortality in patients with multiple sclerosis. Eur J Neurol. 2019 Feb;26(2):342-e23
• Chou IJ, Tanasescu R, Mougin OE, Gowland PE, Tench CR, Whitehouse WP, Gran B, Nikfekr E, Sharrack B, Mazibrada G, Constantinescu CS. 2019 Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging. Sci Rep, 9: 14378.
• Clarke, M.A., Samaraweera, A.P., Falah, Y., Pitiot, A., Allen, C.M., Dineen, R.A., Tench, C.R., Morgan, P.S. and Evangelou, N., 2019. Single Test to ARrive at Multiple Sclerosis (STAR-MS) diagnosis: A prospective pilot study assessing the accuracy of the central vein sign in predicting multiple sclerosis in cases of diagnostic uncertainty. Multiple Sclerosis Journal, p.1352458519882282.
• das Nair, R., de Groot, V., & Freeman, J. (2019). Beyond current research practice: methodological considerations in MS rehabilitation research. Multiple Sclerosis Journal, 25(10), 1337-1347.
• I-Jun Chou, Radu Tanasescu, Olivier E. Mougin, Penny A. Gowland, Christopher R. Tench, William P. Whitehouse, Bruno Gran, Esmaeil Nikfekr, Basil Sharrack, Gordon Mazibrada & Cris S. Constantinescu, 2019. Reduced Myelin Signal in Normal appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging. Sci Rep 9:14378  https://doi.org/10.1038/s41598-019-50928-0.
• Klein, O., das Nair, R., Ablewhite, J., & Drummond, A. (2019). Assessment and management of cognitive problems in people with multiple sclerosis: A National Survey of Clinical Practice. International Journal of Clinical Practice. DOI: 10.1111/ijcp.13300
• Lincoln, N. B., Bradshaw, L. E., Constantinescu, C. S., Day, F., Drummond, A. E., Fitzsimmons, D., … das Nair, R. (2019). Cognitive rehabilitation for attention and memory in people with multiple sclerosis: a randomized controlled trial (CRAMMS). Clinical Rehabilitation. https://doi.org/10.1177/0269215519890378
• Maple PAC, Tanasescu R, Gran B, and Constantinescu CS. A different response to Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infection in UK people with multiple sclerosis (PwMS) compared to controls. 2019. J Infection. pii: S0163-4453(19)30329-9. doi: 10.1016/j.jinf.2019.10.017.
• Marck CH, das Nair R, Grech LB, Borland R, Constantinescu CS. Modifiable risk factors for poor health outcomes in multiple sclerosis: The urgent need for research to maximise smoking cessation success. Mult Scler. 2019 Jun 20:1352458519858730.
• Mexhitaj I, Nyirenda MH, Li R, O'Mahony J, Rezk A, Rozenberg A, Moore CS, Johnson T, Sadovnick D, Collins DL, Arnold DL, Gran B, Yeh EA, Marrie RA, Banwell B, Bar-Or A, 2019. Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis. Brain 142:617-632. doi: 10.1093/brain/awz017.
• Mowry, E.M., Ontaneda, D., Evangelou, N. and Newsome, S.D., 2019. Pragmatic clinical trials for treating relapsing multiple sclerosis. Lancet Neurol. 2019 Dec;18(12):1075. PMID: 31701890
• Papathanasiou A, Tanasescu R, Rocha MF, Singhal S, O’Donoghue MF, Constantinescu CS. 2019. MOG-IgG-associated demyelination: focus on atypical features, brain histopathology and concomitant autoimmunity. J Neurol 2019 doi: 10.1007/s00415-019-09586-5
• Ontaneda D, Tallantyre E, Kalincik T, Planchon SM, Evangelou N. Early highly effective versus escalation treatment approaches in relapsing multiple sclerosis. Lancet Neurol. 2019 Oct;18(10):973-980. PMID: 31375366
• Sinnecker T, Clarke MA, Meier D, et al. Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis. JAMA Neurol. Published online August 19, 2019. doi:10.1001/jamaneurol.2019.2478
• Tallantyre EC, Evangelou N, Bale C, Chaudhry BZ, Gray EH, LaRocca N, Pavitt S, Miller DM, Planchon SM, Ontaneda D, Manzano A. Achieving effective patient and public involvement in international clinical trials in neurology. Neurology: Clinical Practice. 2019 Sep 26:10-212.

2018

• Alrouji M, Manouchehrinia A, Gran B, Constantinescu CS. Effects of cigarette smoke on immunity, neuroinflammation and multiple sclerosis. J Neuroimmunol. 2018 Oct 9. pii: S0165-5728(18)30130-9
• Aram J, Francis A, Tanasescu R, Constantinescu CS. Granulocyte-Macrophage Colony-Stimulating Factor as a Therapeutic Target in Multiple Sclerosis. Neurol Ther. 2018 Dec 1. doi: 10.1007/s40120-018-0120-1. [Epub ahead of print] Review.
• Berti F, Arif Z, Constantinescu CS, Gran B, 2018. Hypothermia in Multiple Sclerosis - beyond the hypothalamus? A case report and review of the literature. Case Rep Neurol Med, 2018 Mar 21;2018:2768493. doi: 10.1155/2018/2768493.
• Chou IJ, Lim SY, Tanasescu R, Al-Radaideh A, Mougin OE, Tench CR, Whitehouse WP, Gowland PA, Constantinescu CS. Seven-Tesla Magnetization Transfer Imaging to Detect Multiple Sclerosis White Matter Lesions. J Neuroimaging. 2018 Mar;28(2):183-190
• Constantinescu CS, Gershkovich P. Therapeutic cannabinoids in multiple sclerosis: immunomodulation revisited. Eur J Neurol. 2018 Jul;25(7):905-906
• Dumitrescu L, Constantinescu CS, Tanasescu R. Recent developments in interferon-based therapies for multiple sclerosis. Expert Opin Biol Ther. 2018 Jun;18(6):665-680
• Dumitrescu L, Constantinescu CS, Tanasescu R. Siponimod for the treatment of secondary progressive multiple sclerosis. Expert Opin Pharmacother. 2018 Dec 5:1-8. doi: 10.1080/14656566.2018.1551363. [Epub ahead of print]
• Francis A & Constantinescu CS. Gastrointestinal influences in multiple sclerosis: Focus on the role of the microbiome. Clin Exp Neuroimmunol, 2018, 9 (Suppl. 1),(2018) 2–12  https://doi.org/10.1111/cen3.12432
• R. Geraldes, O Ciccarelli, F Barkhof, et al Current role of MRI in differentiating multiple sclerosis from its imaging mimics" by Nat Rev Neurol. 2018 Apr;14(4):199-213
• Goodwin, R., Lincoln, N. B., das Nair, R., & Bateman, A. (2018). Evaluation of NeuroPage as a memory aid for people with multiple sclerosis: A randomised controlled trial. Neuropsychological Rehabilitation,  https://doi.org/10.1080/09602011.2018.1447973
• Md J Hossain, E Morandi, R Tanasescu, N Frakich, M Caldano, D Onion, TA Faraj, C Erridge, and B Gran, 2018. The Soluble Form of Toll-Like Receptor 2 Is Elevated in Serum of Multiple Sclerosis Patients: A Novel Potential Disease Biomarker. Front Immunol 9:457.
• Kapoor R, et al (ASCEND investigators), 2018. Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label extension. Lancet Neurol pii: S1474-4422(18)30069-3.
• R.Middleton W.Rodgers J.Chataway et al Validating the portal population of the United Kingdom Multiple Sclerosis Register Multiple Sclerosis and Related Disorders Volume 24, August 2018, Pages 3-10
• E Morandi, R Tanasescu, RE Tarlinton, D Constantin-Teodosiu, and B Gran, 2018. Do antiretroviral drugs protect from multiple sclerosis by inhibiting the expression of MS-associated retrovirus? Front Immunol 9:3092.
• Proctor, B., Moghaddam, N., Evangelou, N., & das Nair, R. (2018). Telephone-supported acceptance and commitment bibliotherapy for people with multiple sclerosis and psychological distress: A pilot randomised controlled trial. Journal of Contextual Behavioral Science, 9, 103-109. ISSN 2212-1447
• Samaraweera APR, Falah Y, Pitiot A, Dineen RA, Morgan PS, Evangelou N. The MRI central vein marker; differentiating PPMS from RRMS and ischemic SVD. Neurol Neuroimmunol Neuroinflamm. 2018 Sep 26;5(6):e496
• Tallantyre EC, Whittam DH, Jolles S, Paling D, Constantinescu C, Robertson NP, Jacob A (Correction to: ) Secondary antibody deficiency: a complication of anti-CD20 therapy for neuroinflammation.. J Neurol. 2018 May;265(5):1123. doi: 10.1007/s00415-018-8833-8.
• Tanasescu R, Constantinescu CS, Tench CR, Manouchehrinia A. Smoking cessation and the reduction of disability progression in Multiple Sclerosis: a cohort study. Nicotine Tob Res. 2018 Apr 2;20(5):589-595

2017

• Barker, A., Lincoln, N. B., Hunt, N., & das Nair, R. (2017). Social Identity in People with Multiple Sclerosis: An Examination of Family Identity and Mood. International Journal of MS Care, DOI: 10.7224/1537-2073.2016-074.
• Bhopale MK, Hilliard B, Constantinescu CS, Phillips SM, Rostami A. DAB₃₈₉IL-2 recombinant fusion toxin effect on lymphocyte- and macrophage-producing cytokine subpopulation cells in experimentally induced demyelinating disease in mice.Immunopharmacol Immunotoxicol. 2017 Dec;39(6):318-329. doi: 10.1080/08923973.2017.1369099. Epub 2017 Sep 20.
• Cerutti C, Edwards LJ, de Vries H E, Sharrack, BM, Nalel DK, Romero, IA. (2017). MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium. Scientific Reports 7:45284.
• Crooks J, Gargaro M, Vacca C, Volpi C, Pirro M, Scalisi G, Turco A, Puccetti P, Rostami AM, Gran B, Fallarino F. Generation of protective immune environment by a CpG type A oligonucleotide in murine models of Multiple Sclerosis. Mediators Inflamm, 2017:1380615. doi: 10.1155/2017/1380615
• Klein, O., Drummond, A., Mhizha-Murira, J., Mansford, L., & das-Nair, R. (2017). Effectiveness of cognitive rehabilitation for people with multiple sclerosis: A meta-synthesis of patient perspectives. Neuropsychological Rehabilitation. DOI:10.1080/09602011.2017.1309323
• Manouchehrinia A, Tanasescu R, Kareem H, Jerca OP, Jabeen F, Shafei R, Breuer J, Neal K, Irving W, Constantinescu CS. Prevalence of a history of prior varicella/herpes zoster infection in multiple sclerosis.  J Neurovirol. 2017 Dec;23(6):839-844
• Mhizha-Murira, J., Drummond, A., Klein, O., & das Nair, R. (2017). Reporting interventions in trials evaluating cognitive rehabilitation in people with Multiple Sclerosis: A systematic review. Clinical Rehabilitation. doi: 10.1177/0269215517722583.
• E Morandi, R Tarlinton, R Tanasescu, and B Gran, 2017. Human Endogenous Retroviruses and Multiple Sclerosis: Causation, Association or After-Effect? Mult Scler J 23(8):1050-1055.
• Morandi E, Jagessar SA, ‘t Hart B, Gran B, 2017. EBV infection empowers human B cells for autoimmunity – Role of autophagy and relevance to multiple sclerosis. J Immunol, 199:435-448. doi: 10.4049/jimmunol.1700178
• Morandi E, Tanasescu R, Tarlinton RE, Constantinescu CS, Zhang W, Tench C, Gran B, 2017. The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis. PLoS One, 12(2):e0172415.
• Proctor, B., Moghaddam, & das Nair, R. (2017). Telephone-psychotherapy in Multiple Sclerosis: A systematic review and meta-analysis. Rehabilitation Psychology. DOI: 10.1037/rep0000182
• Samaraweera APR, Clarke MA, Whitehead A, Falah Y, Driver ID, Dineen RA, Morgan PS, Evangelou N. The central vein sign: Present in MS irrespective of the MRI scanner or T2* sequence at 3T.  J Neuroimaging. 2017 Jan;27(1):114-121
• Tanasescu R, Midgley A, Robins RA, Constantinescu CS.  Decreased Interferon-β induced STAT-4 activation in immune cells and clinical outcome in MS. Acta Neurol Scand 2017 Sep;136(3):233-238
• Zgair A, Lee JB, Wong JCM, Taha DA, Aram J, Di Virgilio D, McArthur JW, Cheng YK, Hennig IM, Barrett DA, Fischer PM, Constantinescu CS, Gershkovich P. Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. Sci Rep. 2017 Nov 6;7(1):14542. doi: 10.1038/s41598-017-15026-z.
• Zhang Y, Li X, Ciric B, Ma CG, Gran B, Rostami A, Zhang GX, 2017. Effect of Fingolimod on Neural Stem Cells: A Novel Mechanism and Broadened Application for Neural Repair. Mol Ther 25:401-415.

2016

• 't Hart BA, Kap YS, Morandi E, Laman JD, Gran B, 2016. EBV Infection and Multiple Sclerosis: Lessons from a Marmoset Model. Trends Mol Med S1471-4914(16)30149-6.
• Chou IJ, Wang HS, Whitehouse WP, Constantinescu CS. Paediatric Multiple Sclerosis: Update on Diagnostic Criteria, Imaging, Histopathology and Treatment Choices. 2016 Curr Neurol Neurosci Rep Jul;16(7):68. doi: 10.1007/s11910-016-0663-4.
• Coclitu C, Constantinescu CS, Tanasescu R. Curr Neurol Neurosci Rep. 2016 Jul;16(7):68. The future of multiple sclerosis treatments. Expert Rev Neurother. 2016 Dec;16(12):1341-1356.
• Constantinescu SE, Constantinescu CS. Laquinimod (ABR-215062) for the treatment of relapsing multiple sclerosis.  Expert Rev Clin Pharmacol. 2016 Jan;9(1):49-57. doi: 10.1586/17512433.2016.1108189. Epub 2015 Nov 4.
• Cronin MJ, Wharton S, Al-Radaideh A, Constantinescu C, Evangelou N, Bowtell R, Gowland PA.  A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field. MAGMA. 2016 Jun;29(3):543-57.
• das Nair R, Martin KJ, Lincoln NB. (2016). Memory rehabilitation for people with multiple sclerosis. Cochrane Database of Systematic Reviews, Issue 3. Art. No.: CD008754. DOI: 10.1002/14651858.CD008754.pub3.
• das Nair, R., Cogger, H., Worthington, E., & Lincoln, N.B. (2016). Cognitive rehabilitation for memory deficits after stroke (An Updated Review). Stroke. DOI: 10.1161/STROKEAHA.116.015377
• das Nair, R., Cogger, H., Worthington, E., & Lincoln, N.B. (2016). Cognitive rehabilitation for memory deficits after stroke. Cochrane Database of Systematic Reviews. Issue 9. Art. No.: CD002293. DOI: 10.1002/14651858.CD002293.pub3.
• Fallarino F, Gargaro M, Mondanell G, Downer EJ, Hossain MJ, Gran B, 2016. Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE. Methods Mol Biol. 2016; 1390:383-411.
• Harrison, A., das Nair, R., & Moss-Morris, R. (2016). Operationalising cognitive fatigability in Multiple Sclerosis: A Gordian knot that can be cut? Multiple Sclerosis Journal. DOI: 10.1177/1352458516681862
• Hossain MJ, Tanasescu R, Gran B, 2016. Innate immune regulation of autoimmunity in multiple sclerosis: Focus on the role of Toll-like receptor 2. J Neuroimmunol S0165-5728(16)30448-9.
• Jagessar SA, Holtman IR, Hofman S, Morandi E, Heijmans N, Laman JD, Gran B, Faber BW, van Kasteren SI, Eggen BJ, 't Hart BA, 2016. Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein. J Immunol 197:1074-88.
• X Li, Y Zhang, Y Yan, B Ciric, CG Ma, B Gran, M Curtis, AM Rostami, and Guang-Xian Zhang, 2016. Neural Stem Cells Engineered to Express Three Therapeutic Factors Mediate Recovery from Chronic Stage CNS Autoimmunity. Mol Ther doi: 10.1038/mt.2016.104. PMID: 27203442
• Manouchehrinia A, Tanasescu R, Tench CR, Constantinescu CS.  Mortality in multiple sclerosis: meta-analysis of standardised mortality ratios.  J Neurol Neurosurg Psychiatry. 2016 Mar;87(3):324-31   pii: jnnp-2015-310361. doi: 10.1136/jnnp-2015-310361.
• Mougin O, Abdel-Fahim R, Dineen R, Pitiot A, Evangelou N, Gowland P.  Imaging gray matter with concomitant null point imaging from the phase sensitive inversion recovery sequence. Magn Reson Med. 2016 Nov;76(5):1512-1516
• Rodríguez Cruz PM, Matthews L, Boggild M, Cavey A, Constantinescu CS, Evangelou N, Giovannoni G, Gray O, Hawkins S, Nicholas R, Oppenheimer M, Robertson N, Zajicek J, Rothwell PM, Palace J. Time- and Region-Specific Season of Birth Effects in Multiple Sclerosis in the United Kingdom. JAMA Neurol. 2016 Aug 1;73(8):954-60.
• Traboulsee AL, Cornelisse P, Sandberg-Wollheim M, Uitdehaag BMJ, Kappos L, Jongen PJ, Constantinescu CS, Verdun di Cantogno E, Li, DKB. Prognostic factors for long-term outcomes in relapsing remitting multiple sclerosis. Mult Scler J –Exp Transl Clin 2016 2: 1-9.
• Tench CR, Tanasescu R, Cottam WJ, Constantinescu CS, Auer DP. Coordinate based meta-analysis does not show grey matter atrophy in narcolepsy. Neurosci Biobehav Rev. 2016 Nov 5. pii: S0149-7634(16)30383-9 (letter)
• Zgair A, Wong JC, Lee JB, Mistry J, Sivak O, Wasan KM, Hennig IM, Barrett DA, Constantinescu CS, Fischer PM, Gershkovich P. Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines. Am J Transl Res. 2016 Aug 15;8(8):3448-59.

2015

• ‘t Hart B, Van Kooyk Y, Geurts JG, Gran B, 2015. The non-human primate autoimmune encephalomyelitis model; a bridge between mouse and man. Ann Clin Transl Neurol 2:581-93.
• Al-Radaideh A, Mougin OE, Lim SY, Chou IJ, Constantinescu CS, Gowland P. Histogram analysis of quantitative T1 and MT maps from ultrahigh field MRI in clinically isolated syndrome and relapsing-remitting multiple sclerosis. NMR Biomed. 2015 Nov;28(11):1374-82.
• Chivers TR, Constantinescu CS, Tench CR. MRI-Based Measurement of Brain Stem Cross-Sectional Area in Relapsing-Remitting Multiple Sclerosis. J Neuroimaging. 2015 Nov-Dec;25(6):1002-6. doi: 10.1111/jon.12244. Epub 2015 Apr 19.
• Constantinescu CS, Asher A, Fryze W, Kozubski W, Wagner F, Aram J, Tanasescu R, Korolkiewicz RP, Dirnberger-Hertweck M, Steidl S, Libretto SE, Sprenger T, Radue EW. Randomized phase 1b trial of MOR103, a human antibody to GM-CSF, in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2015 May 21;2(4):e117. doi: 10.1212/NXI.0000000000000117. eCollection 2015 Aug.
• K Cook, J Crooks, K Hussain, K O’Brien, M Braitch, H Kareem, C Constantinescu, K Robinson and B Gran, 2015. Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis. Front Microbiol 6:52. doi: 10.3389/fmicb.2015.00052
• das Nair, R. (2015). Evaluating cognitive rehabilitation in multiple sclerosis: On the bumpy road to establishing evidence. Neurodegenerative Disease Management, 5(6), 473-478.
• das Nair, R., Kontou, E., Smale, K., Barker, A., & Lincoln, N.B. (2015). Comparing individual and group intervention for psychological adjustment in people with multiple sclerosis: A feasibility randomised controlled trial. Clinical Rehabilitation. DOI: 10.1177/0269215515616446.
• Goodwin, R., Lincoln, N., das Nair, R., & Bateman, A. (2015). External memory aids for memory problems in people with multiple sclerosis: a systematic review. Neuropsychological Rehabilitation. Nov 26:1-22. [Epub ahead of print]
• Hossain MJ, Tanasescu R, Gran B, 2015. TLR2 – an innate immune checkpoint in multiple sclerosis. Oncotarget 6:35131-2. PMID 26459385
• Jean-Gilles L, Braitch M, Latif ML, Aram J, Fahey A, Edwards L, Robins RA, Tanasescu R, Tighe P, Showe L, Gran B, Alexander S, Chapman V, Kendall D, Constantinescu C, 2015. Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells. Acta Physiol 214:63-74; PMID: 25690155
• Khan UT, Tanasescu R, Constantinescu CS. PEGylated IFNβ-1a in the treatment of multiple sclerosis. Expert Opin Biol Ther. 2015 Jul;15(7):1077-84. doi: 10.1517/14712598.2015.1053206. Epub 2015 Jun
• Nyirenda MH, Morandi E, Vinkemeier U, Constantin-Teodosiu D, Drinkwater S, Mee M, King L, Podda G, Zhang GX, Ghaemmaghami A, Constantinescu CS, Bar-Or A, Gran B. TLR2 stimulation regulates the balance between regulatory T cell and Th17 function: a novel mechanism of reduced regulatory T cell function in multiple sclerosis. J Immunol. 2015 15;194(12):5761-74. doi: 10.4049/jimmunol.1400472. Epub 2015 May 15.
• Manouchehrinia A, Edwards LJ, Roshanisefat H, Tench CR, Constantinescu CS. Multiple sclerosis course and clinical outcomes in patients with comorbid asthma: a survey study. BMJ Open. 2015 May 20;5(5):e007806. doi: 10.1136/bmjopen-2015-007806.
• Morandi E, Tarlinton R, Gran B, 2015. Multiple Sclerosis between Genetics and Infections: Human Endogenous Retroviruses in Monocytes and Macrophages. Front. Immunol 24 December 2015  http://dx.doi.org/10.3389/fimmu.2015.00647
• Tanasescu R, Constantinescu CS. Helminth therapy for MS. Curr Top Behav Neurosci. 2015;26:195-220.
• J Vilisaar, K Kawabe, M Braitch, J Aram, Y Furtun, AJ Fahey, M Chopra, R Tanasescu, PJ Tighe, B Gran, C Pothoulakis, and CS Constantinescu, 2015. Reciprocal regulation of Substance P and IL-12/IL-23 and the associated cytokines IFNγ/IL-17: a perspective on the relevance of this interaction to multiple sclerosis. J Neuroimmune Pharmacol  10:457-67; PMID 25690155
• Welton T, Kent DA, Auer DP, Dineen RA. Reproducibility of Graph-Theoretic Brain Network Metrics: A Systematic Review. Brain Connect. 2015 May;5(4):193-202
• Welton T, Constantinescu CS, Auer DP, Dineen RA. Functionally-Relevant White Matter Degradation in Multiple Sclerosis: A Tract-Based Spatial Meta-Analysis. Radiology. 2015 Apr;275(1):89-96
• Zgair A, Wong JC, Sabri A, Fischer PM, Barrett DA, Constantinescu CS, Gershkovich P. Development of a simple and sensitive HPLC-UV method for the simultaneous determination of cannabidiol and Δ(9)-tetrahydrocannabinol in rat plasma. J Pharm Biomed Anal. 2015 Oct 10;114:145-51
• Y Zhang, X Li, B Ciric, C Ma, B Gran, A.M. Rostami, and GX Zhang. 2015. Therapeutic effect of baicalin on experimental autoimmune encephalomyelitis is mediated by SOCS3 regulatory pathway. Sci Rep 5:17407. doi: 10.1038/srep17407; PMID 26616302

2014

• Barker, A., das Nair, R., Lincoln, N.B., & Hunt, N. (2014). Social Identity in people with Multiple Sclerosis: A Meta-synthesis of Qualitative Research. Social Care and Neurodisability, 5(4), 256-267. DOI 10.1108/SCN-05-2014-0009.
• Carr, S., das Nair, R., Schwartz, A., & Lincoln, N.B. (2014). Group Memory Rehabilitation for People with Multiple Sclerosis: A pilot randomised controlled trial. Clinical Rehabilitation, 28(6), 552-561. DOI : 10.1177/0269215513512336
• Constantinescu CS, Gran B, 2014. The essential role of T cells in multiple sclerosis: A reappraisal. Biomed J 37:34-40.
• DC Fitzgerald, K O'Brien, A Young, Z Fonseca-Kelly, A Rostami and B Gran, 2014. Interferon Regulatory Factor (IRF) 3 is critical for the development of Experimental Autoimmune Encephalomyelitis. J Neuroinflammation, 11:130 (PMID: 25069698).
• F Hartmann, M Khademi, J Aram, S Ammann, I Kockum, C Constantinescu, B Gran, F Piehl, T Olsson, L Codarri, and B Becher, 2014. Multiple Sclerosis-associated IL2RA Polymorphism Controls GM-CSF Production in Human TH Cells. Nat Commun 5:5056.
• A Mahadeva, R Tanasescu, B Gran, 2014. Urinary tract infections in multiple sclerosis: under-diagnosed and under-treated? A clinical audit at a large University hospital. Am J Clin Exp Immunol 3:57-67.
• Martin, K-J, Lincoln, N. & das Nair, R. (2014). Evaluation of a Group-Based Memory Rehabilitation for People with Multiple Sclerosis: A Sub-Group Analysis of the ReMiND Randomised Controlled Trial. International Journal of Therapy & Rehabilitation, 21(12): 590-596.
• Smale, K., Carr, S.E., Schwartz, A., das Nair, R., & Lincoln, N. (2014). An evaluation of treatment integrity in a randomised controlled trial of memory rehabilitation for people with multiple sclerosis. Clinical Rehabilitation. pii: 0269215514548733. [Epub ahead of print]

2013

• Humphreys I, Drummond AER, Phillips C, Lincoln NB. Cost-effectiveness of a psychological support group for people with Multiple Sclerosis. Clinical Rehabilitation 2013. Jul 8. [E pub ahead of print] DOI; 10.1177/0269215513488608
• Wilkinson, H., & das Nair, R. (2013). The Psychological Impact of Living with an Unpredictable Illness: A Meta-Synthesis of Qualitative Research Literature in Multiple Sclerosis. British Journal of Neuroscience Nursing, 9(4), 172-178.

2012

• Dineen RA, Bradshaw CM, Constantinescu CS, Auer DP.  Extra-hippocampal subcortical limbic involvement predicts episodic recall performance in multiple sclerosis.  PLoS One. 2012;7(10):e44942.
• Holmes J, Ford E, Yuill F, Drummond AER and Lincoln N. Attendance at a psychological support group for people with MS. Disability & Rehabilitation 2012; 34 (15): 1323-1327.

2011

• Constantinescu CS, Niepel G, Patterson M, Judd A, Braitch M, Fahey AJ, Harikrishnan S, Edwards LJ, Tench CR, Bennett GW, Ghatei M. (2011). Orexin A (hypocretin-1) levels are not reduced while cocaine / amphetamine regulated transcript levels are increased in the cerebrospinal fluid of patients with multiple sclerosis: no correlation with fatigue and sleepiness. Journal of Neurological Sciences, vol 307(1-2) pp127-131
• Lincoln, N.B., Yuill, F., Holmes, J., Drummond, A., Constantinescu, C., Armstrong, S., and Phillips, C.  Evaluation of an adjustment group for people with multiple sclerosis and low mood: a randomized controlled trial. Multiple Sclerosis, Published online before print May 25, 2011, doi: 10.1177/1352458511408753 Multiple Sclerosis Journal 17, (10) 1250-1257.