3rd December 2025

Online via MS Teams

The 5th Annual Symposium on state of the art understanding of the neurobiology of Psychosis and Schizophrenia with world leading experts in the field, from The Institute of Mental Health's Centre for Translational Neuroscience.

About the event:

Schizophrenia and Psychotic Disorders are amongst the most pressing mental health enigmas of the current age. Although several advances have been made in recent years, no unifying theory of the neurobiological underpinnings currently exists.

Join us at our 2025 seminar as we bring together leading academics to allow us to understand cutting-edge advances from world class experts in the field. Previous proceedings of the seminars can be found in the Oxford Academic Schizophrenia Bulletin and Comprehensive Psychiatry.

Last years symposium can be viewed here.

Programme was as follows:

• Welcome and introduction - Dr Musa Sami (Chair)
• The Mechanisms of Persisting Disability in Schizophrenia - Imprecise Predictive Coding via Corticostriatothalamic-Cortical Loop Dysfunction - Professor Peter Liddle, University of Nottingham
• Understanding the development of psychotic symptoms in a neurocomputational framework - Dr Albert Powers, Yale University
• Xanomeline-trospium for schizophrenia: the clinician's experience - Dr Sheharyar Sarwar, Shephard Pratt, Baltimore Campus
• Circuit-based treatments for psychosis - Professor Donald Goff, Nathan Kline Institute at NYU Grossman School of Medicine
• Synaptic Density Imaging as a new biomarker for psychosis - Professor Romina Mizrahi, McGill University
• Panel Discussion - All speakers, plus Prof Peter Liddle and Dr Musa Sami and Joined by Professor Lena Palaniyappan, McGill University

Watch the symposium back:

Professor Peter Liddle

 Dr Albert Powers

 
Dr Sheharyar Sarwar

 
Professor Don Goff

 
Professor Romina Mizrahi